Menstrual Disorders PMS & PMDD An Overview of PMS Premenstrual syndrome (PMS) affects women of all ages By Tracee Cornforth Tracee Cornforth LinkedIn Tracee Cornforth is a freelance writer who covers menstruation, menstrual disorders, and other women's health issues. Learn about our editorial process Updated on July 30, 2021 Learn more</a>." data-inline-tooltip="true"> Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Anita Sadaty, MD Medically reviewed by Anita Sadaty, MD Facebook LinkedIn Twitter Anita Sadaty, MD, is a board-certified obstetrician-gynecologist at North Shore University Hospital and founder of Redefining Health Medical. Learn about our Medical Expert Board Print Table of Contents View All Table of Contents Symptoms Causes Diagnosis Treatment Premenstrual syndrome (PMS), is a group of symptoms that occurs before the first day of a woman's period. Some women experience mild abdominal cramps for a few hours, while others can experience severe pain and mood swings for up to two weeks before their period starts. PMS is often diagnosed based on the timing of the symptoms. When the effects are especially burdensome, hormone levels or imaging tests may be needed to determine whether a woman has a health condition. There are natural therapies and medical treatments that can help alleviate the effects of PMS, and you can talk to your healthcare provider to determine which approach is best for you. Charday Penn / Getty Images Symptoms The premenstrual phase is usually a few days before a woman's period, but it can begin up two weeks before the start of menstruation. For symptoms to be considered part of PMS, they must occur within the two weeks before a woman's period and should not be present the rest of the month. PMS can begin at any age once a woman begins having menstrual periods. There are a number of physical, emotional, and cognitive effects that can occur as part of PMS. Common symptoms of PMS include: Uterine cramps Abdominal bloating Sore, tender breasts Food cravings Irritability Tearfulness Mood swings Sadness Anxiety Angry outbursts Headaches or migraines Trouble sleeping Fatigue Change in sexual desire Weight gain Muscle aches Slight swelling of the arms or legs Digestive symptoms such as nausea, diarrhea, or constipation Exacerbation of digestive disorders, such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) While you may experience some of these effects, it is unlikely that you will experience all of the different symptoms that can occur with PMS. Many teenagers experience PMS, and each woman's symptoms may change as she gets older. For example, a woman who may be prone to PMS-associated angry outbursts for years might not experience them anymore but could begin having abdominal cramps and weight gain in the days before her period. Hot Flashes Before Period: What You Need to Know Complications Some women experience especially distressing effects of PMS that can interfere with relationships, work, and overall well being. Serious effects of PMS include: Problems with marriage or relationshipDifficulty parentingDecreased work or school performanceLoss of interest in socializingSuicidal thoughts If you experience depression with your PMS, you may have a form known as premenstrual dysphoric disorder (PMDD). Causes The effects of PMS are caused by hormonal changes that occur during a woman's menstrual cycle. Estrogen and progesterone are the main hormones in a woman's body. These hormones fluctuate throughout a woman's menstrual cycle. Before a woman's period, estrogen levels drop and progesterone levels rise. There is also a pattern of cyclical physiologic shifts that occur throughout the body in the weeks and days before menstruation, including metabolic variations, alterations in neurotransmitters, and vascular changes. The neurotransmitters serotonin (associated with mood) and gamma-aminobutyric acid (GABA, associated with rest) are most closely linked with PMS. All of these physiologic shifts, as well as the hormonal patterns, induce symptoms of PMS. Some of the hormonal and physiologic patterns of a menstrual cycle and their effects on PMS include: Hormone changes cause breast soreness and swellingHormone changes trigger uterine contracting (which causes abdominal/uterine cramping)Metabolic variations affect appetite, weight, swelling, and energy levelsNeurotransmitter alterations affect mood, sleep, digestive symptoms, and can induce migrainesVascular changes can affect migraines and may cause swelling of the arms and legs Experts suggest that the alterations in estrogen and progesterone initiate the other physiologic effects of PMS. While most women have very similar patterns during the menstrual cycle, there are some minor variations between women—which is why not every woman experiences the same exact symptoms of PMS. Diagnosis There are several screening tools used in the diagnosis of PMS. Generally, healthcare providers use a medical history or questionnaire to diagnose this condition. There are no blood tests or other diagnostic tests that can verify a diagnosis of PMS. Among the criteria for diagnosing PMS, your symptoms must disappear during or immediately after your period and not show up again until two weeks before your next period. And they must be unrelated to medications (including hormone replacement), alcohol, or drugs. You can keep a calendar to help you keep track of the timing of your symptoms. Menstrual Cycle Calendar The easiest way to determine if you have PMS is to keep track of your symptoms for two or three months on a standard calendar. A menstrual cycle calendar will help you and your healthcare provider know if you are having cyclical symptoms that correspond with your menstrual cycle. Take these steps to fill out a menstrual cycle calendar: The first day you begin bleeding, write day 1 on your calendarNote any symptoms you experience on that day and rate each on a scale of one to 10Do this every day for two or three months How Keeping Track of Your Menstrual Cycle Can Help Your Health True symptoms of PMS do not begin until after day 13, so any symptoms you experience earlier in your cycle may have another cause. However, you should still include any symptoms you experience on days 1 to 13 on your calendar. PMDD PMDD is a severe form of PMS that affects approximately 3% to 8% of women who menstruate. According to the Diagnostic and Statistical Manual of Mental Disorders, in order to be diagnosed with PMDD a woman must experience at least five of the following symptoms during the premenstrual phase of her cycle, and not at other times: Feelings of sadness or hopelessness, or suicidal thoughtsSevere stress, tension, or anxietyPanic attacksInappropriate mood swings and bouts of cryingConstant irritability or anger that affects other peopleLoss of interest in normal daily activities and relationshipsInability to concentrate or focusLethargy Binge eating Differential Diagnosis You may need a diagnostic evaluation to search for hormonal or uterine problems if you have extreme physical symptoms and/or irregular bleeding. This type of evaluation can include blood tests that examine hormone levels and imaging tests that examine the uterus or ovaries. If your symptoms do not follow a cyclical pattern, your healthcare provider may consider other conditions such as depression, anxiety, gastrointestinal disease, or thyroid disease. Treatment There are ways to manage PMS. Some women benefit from using supplements or over-the-counter (OTC) therapies, while others may need prescription medications. Lifestyle approaches can be useful as well. Whether or not you need treatment depends on the severity of your symptoms and their effect on your life. You can discuss your symptoms with your healthcare provider, who can recommend the best treatment for you. Treatments for PMS can include: OTC pain medication: If you have cramps, headaches, or breast tenderness you may benefit from medications such as Advil (ibuprofen) or Tylenol (acetaminophen). Supplements: Some women become deficient in vitamins, such as vitamin C, magnesium or vitamin B12. Changes in appetite can cause these nutritional deficiencies, and supplements may help with symptoms of PMS, as well as with symptoms of nutritional deficiency. Prescription pain medication: If you have severe cramps, migraines, or depression, you may be given a prescription medication to alleviate your symptoms. Hormonal therapy: For some women, hormone therapy with oral contraceptives, estrogen replacement, or progesterone cream can help reduce the effects of PMS. Keep in mind that hormones can have major effects on fertility and may be contraindicated in women who are at risk of breast, ovarian, or uterine cancer. Acupuncture or acupressure: Research suggests that these alternative therapies may reduce some symptoms of PMS for some women. Keep in mind that your PMS symptoms can change when you are using birth control, and you may need a new treatment approach when your symptoms change. Lifestyle Adjustments There are also non-medical approaches you can take to help reduce some of your symptoms. Women who have mild cramps may experience relief by placing an ice pack on the abdomen for a few minutes. Women who have mild mood swings may benefit from talking to a counselor or a trusted friend. Habits such as exercising, writing in a journal, or even just being aware that the mood swings are hormonal can help prevent outbursts that can damage relationships. A Word From Verywell PMS is very common. While most women can function perfectly fine at all times of the month, the condition can be distressing for some women. If PMS is interfering with your life, it is important that you talk to your healthcare provider to try to seek relief of your physical and emotional symptoms so that you can function at your best. What Is the Period Flu? 12 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Office on Women's Health, U.S. Department of Health and Human Services. Premenstrual syndrome (PMS). Hantsoo L, Epperson CN. Premenstrual Dysphoric Disorder: Epidemiology and Treatment. Curr Psychiatry Rep. 17(11):87. doi:10.1007/s11920-015-0628-3 Bäckström T, Andreen L, Birzniece V, et al. The Role of Hormones and Hormonal Treatments in Premenstrual Syndrome. CNS Drugs. 17(5):325-342. doi:10.2165/00023210-200317050-00003 Rapkin AJ, Akopians AL. Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorder. Menopause Int. 18(2):52-59. doi:10.1258/mi.2012.012014 Draper CF, Duisters K, Weger B, et al. Menstrual cycle rhythmicity: metabolic patterns in healthy women. Sci Rep. 8(1):14568. doi:10.1038/s41598-018-32647-0 Wideman L, Montgomery MM, Levine BJ, Beynnon BD, Shultz SJ. Accuracy of calendar-based methods for assigning menstrual cycle phase in women. Sports Health. 5(2):143-149. doi:10.1177/1941738112469930 Reid RL, Soares CN. Premenstrual Dysphoric Disorder: Contemporary Diagnosis and Management. J Obstet Gynaecol Can. 40(2):215-223. doi:10.1016/j.jogc.2017.05.018 American Psychiatric Association. DSM-5 Update. Supplement to Diagnostic and Statistical Manual of Mental Disorders. 5th Edition. Johnson SR. Premenstrual Syndrome, Premenstrual Dysphoric Disorder, and Beyond: A Clinical Primer for Practitioners. Obstet Gynecol. 104(4):845-859. doi:10.1097/01.AOG.0000140686.66212.1e Kaewrudee S, Kietpeerakool C, Pattanittum P, Lumbiganon P. Vitamin or mineral supplements for premenstrual syndrome. Cochrane Database Syst Rev. 2018(1):CD012933. doi:10.1002/14651858.CD012933 Usman SB, Indusekhar R, O'Brien S. Hormonal management of premenstrual syndrome. Best Pract Res Clin Obstet Gynaecol. 22(2):251-260. doi:10.1002/14651858.CD012933 Armour M, Ee CC, Hao J, Wilson TM, Yao SS, Smith CA. Acupuncture and acupressure for premenstrual syndrome. Cochrane Database Syst Rev. 8:CD005290. doi:10.1002/14651858.CD005290.pub2 Additional Reading Henz A, Ferreira CF, Oderich CL, Gallon CW, Castro JRS, Conzatti M, et al. Premenstrual Syndrome Diagnosis: A Comparative Study between the Daily Record of Severity of Problems (DRSP) and the Premenstrual Symptoms Screening Tool (PSST). Rev Bras Ginecol Obstet. 40(1):20-25. doi: 10.1055/s-0037-1608672. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit