Healthy Aging 8 Top Causes of Excess Mortality in the US By Sharon Basaraba Sharon Basaraba Twitter Sharon Basaraba is an award-winning reporter and senior scientific communications advisor for Alberta Health Services in Alberta, Canada. Learn about our editorial process Updated on January 26, 2020 Learn more</a>." data-inline-tooltip="true"> Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Keri Peterson, MD Medically reviewed by Keri Peterson, MD Facebook LinkedIn Twitter Keri Peterson, MD, is board-certified in internal medicine and has her own private practice on the Upper East Side of Manhattan. She holds appointments at Lenox Hill Hospital and Mount Sinai Medical Center. Learn about our Medical Expert Board Print Excess mortality is the number of deaths caused by a specific disease, condition, or exposure to harmful circumstances such as radiation, environmental chemicals, or natural disaster. It's a measure of the deaths which occurred over and above the regular death rate that would be predicted (in the absence of that negative defined circumstance) for a given population. Alexander Spatari / Getty Images Causes of Excess Mortality in the US According to the World Health Organization, excess mortality can be expressed as a mortality rate—which is the risk of dying from that condition in a specific population—or a total number of excess deaths. The following causes are major factors for excess mortality in this country: Heart Disease Heart disease is the leading cause of excess mortality in many cities in the United States, though rates have been declining year over year. The CDC reports about 610,000 people die of heart disease in the U.S. every year—that’s one in every four deaths. Socioeconomic Status Socioeconomic status is an avoidable factor for excess mortality. Though who have a higher income, more education, or those who work have a longer lifespan than those with a lower socioeconomic status. Inner-City Dwelling People living in poverty-stricken urban areas die sooner than their poor counterparts in rural areas. A study in the American Journal of Public Health found rehabilitating housing may improve the conditions and lessen the excess mortality in urban areas. Access to healthcare is also a contributing factor to excess mortality in inner-city areas. Cancer Heart disease and cancer combined represent over 50% of premature deaths making it a massive source of excess mortality. Murder/Suicide While murder in impoverished communities bears greatly on excess mortality, when paired with the national rates of suicide, it accounts for a great number of premature deaths. Many suicide attempts are due to alcohol and drug abuse, as well as those suffering from mental health issues. Physical Inactivity Given the prevalence of chronic diseases like diabetes, high blood pressure, and heart disease, and the fact that physical inactivity is risk factors for these chronic diseases, lack of exercise is a source of excess mortality in the U.S. Body Mass Index (BMI) To go along with physical inactivity, the three chronic diseases mentioned above are more prevalent in people who have a BMI beyond normal weight. That is, those who are overweight, obese, or morbidly obese have excess mortality when compared to those of normal weight. Divorce and Separation Surprisingly, uncoupled people have excess mortality compared to married people who live longer. However, this protective factor is more pronounced for men as single women have a much smaller rate of excess mortality than married women. There are other factors of excess mortality including traffic accidents, social support indicators and the like, but the above are the most widely researched and established contributors to excess mortality. Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Geronimus AT, Bound J, Colen CG, Ingber LB, Shochet T. Urban/rural differences in excess mortality among high poverty populations: Evidence from the Harlem Health Survey and Pitt County. Economic Research Initiative on the Uninsured Working Paper Series. Haentjens P, Magaziner J, Colón-Emeric CS, Vanderschueren D, Milisen K, Velkeniers B, Boonen S. Meta-analysis: Excess mortality after hip fracture among older women and men. Ann Intern Med. 2010 Mar 16;152(6):380-90. doi:10.7326/0003-4819-152-6-201003160-00008 Excess Mortality. World Health Organization Glossary of Humanitarian Terms. See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit