Cancer Colon Cancer The Function of the Colon By Julie Wilkinson, BSN, RN Julie Wilkinson, BSN, RN LinkedIn Julie Wilkinson is a registered nurse and book author who has worked in both palliative care and critical care. Learn about our editorial process Updated on October 28, 2021 Learn more</a>." data-inline-tooltip="true"> Medically reviewed Verywell Health articles are reviewed by board-certified physicians and healthcare professionals. These medical reviewers confirm the content is thorough and accurate, reflecting the latest evidence-based research. Content is reviewed before publication and upon substantial updates. Learn more. by Chris Vincent, MD Medically reviewed by Chris Vincent, MD LinkedIn Chris Vincent, MD, is a licensed physician, surgeon, and board-certified doctor of family medicine. Learn about our Medical Expert Board Print What is the colon? The colon is a vital part of your personal plumbing system. The tubular organ works around the clock to remove waste products from your body. As part of the digestive system, the colon works alongside organs such as the stomach and small intestine to remove stool and maintain your fluid and electrolyte balance. This photo contains content that some people may find graphic or disturbing. See Photo Sebastian Kaulitzki / Getty Images Can You Live Without a Colon? Although it is an amazing organ, it is possible to live without a colon. People have portions of their colon removed in surgery every day—surgical bowel resection is one of the treatment options for colon cancer. However, all six feet of your colon, also called the large intestine, serve a purpose. The majority of the nutrients you eat are absorbed in the small intestine well before the "food" reaches your colon. The colon’s primary job is to form the one-and-a-half quarts of fluid (the food you ingested mixed with digestive juices) into a firm stool for passage out of the body. The colon must reabsorb water and electrolytes to form a stool. This is why, when you are dehydrated, you can get constipated and your stool may become hard and difficult to pass. The colon is pulling more fluid from the stool for your body to use. Anatomy of the Colon The colon is not labeled very creatively—most of the labels for the colon correspond to their anatomical location and flow of stool. Your large intestine is broken down into six sections including the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and the rectum. The colon begins at the end of the small intestine, where it is called the cecum, and ends at the rectum. Cancers of the large intestine are casually referred to as colon, rectal or colorectal cancer. The cecum is anatomically located in the lower right sight of your abdomen approximately where your appendix is attached. The cecum is the widest part of your entire colon and is approximately 5 centimeters long, or a third as long as a pen. Between 15 and 20 percent of all colon cancers occur in the cecum. The ascending colon heads up vertically from the cecum to the transverse colon. The juncture between the cecum and transverse colon is called the right colic flexure, or the hepatic flexure for its proximity to your liver (hepatic system). Anatomically, the ascending colon is about 10 centimeters long and is seated on the right side of your abdomen. The transverse colon connects your ascending and descending colon, traveling lengthwise across your abdomen. The transverse colon lies close to your stomach, liver, and gallbladder and is approximately 50 centimeters long. The descending colon begins at the left colic flexure, also known as the splenic flexure for its proximity to the spleen. This portion of your colon lies in the left side of your abdomen, connecting your transverse colon to your sigmoid colon. The descending colon is approximately 10 centimeters long. The sigmoid colon makes up the last 50 centimeters of the colon leading to the rectum and typically has an 'S' curve or shape to it. Roughly 20 to 25 percent of all colon cancers originate in the distal colon, which includes the descending and sigmoid colon The rectum is the final portion of your large intestine leading to the anus. The digestive process has completely finished by the time stool reaches the rectum, where it waits to be passed as a bowel movement. About 25 to 30 percent of cancers originate in this 15-centimeter piece of the large intestine. A tortuous colon is one that is longer than normal. In this relatively rare condition, in order for this longer tube to fit in your abdomen, the colon ends up with extra twists and turns. Quick Look at a Colon Section The colon is composed of four layers, each with a specific function. When a diagnosis of colon cancer is made, the pathologist will determine what layer cancer has reached (such as the innermost or outermost layer) to help determine the staging of your cancer. The majority of colorectal cancers will start in the innermost layer, called the mucosa, and spread toward the outermost layer, or the serosa, of the colon over time if untreated. Starting at the innermost layer of the colon, the layers include the: Mucosa: Divided into three sub-tissues, the mucosa surface is called the epithelium, where the most colon and rectal cancers originate. The mucosa provides a lubricant, which helps aid in the passage of stool through the colon. Submucosa: The next layer of your colon, which is rich in blood vessels and nerves. The submucosa is a connective tissue layer connecting the mucosa to the next muscle layer. Muscularis Propria: The third layer is composed of opposing layers of muscle fibers—a set that runs horizontally and a set that runs around the colon. Once cancers reach through this layer, there is an increased chance that they can metastasize to other parts of the body. Serosa: The outermost layer of your colon. When cancer spreads through the serosa it has left the colon and metastasized. Keeping Your Colon Happy Your colon is a simple organ with simple needs. Keep it hydrated, clean, and get routine screening exams to check the inner lining for polyps or growths that can precede cancer. Diets high in fat, sugar and excessive red meat consumption (more than 18 ounces a week) may increase your risk for colon cancer. Smoking, obesity, and excessive alcohol consumption may also adversely affect your colon’s health. Help your colon function at its best by: Eating a high-fiber diet rich in whole grains, fruits, and vegetables appears to prevent distal colon cancerDrinking plenty of fresh water dailyLimiting red meat and processed meat (hot dogs) consumptionGet daily exerciseStop using tobacco products including cigarettes and snuffLimit your alcohol intakeTalk to your healthcare provider about a daily multivitamin if your diet is poorLearn more about screening exams to monitor your colon’s health It’s never too late to start learning about your colon and taking a proactive stand toward keeping it healthy. Early detection of colon cancer saves lives—learning more about your colon and keeping it healthy could save yours. Frequently Asked Questions What is the sigmoid colon? The sigmoid colon is the last part of the colon, connecting the descending colon to the rectum. It is relatively S-shaped and gets its name from the Greek letter sigma. Its primary function is to absorb water, vitamins, and some minerals from undigested food particles. Where is the colon located? The colon is found in the abdomen, below the stomach. The first part of the colon, the cecum, is in the lower right part of the abdomen. From there, the colon extends upward to beneath the ribcage, across the upper abdomen from right to left, then down the left side to the anus. Learn More: The Anatomy of the Colon (Large Intestine) What are the parts of the colon? The colon, or large intestine, is made up of six parts. These include the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and the rectum. 6 Sources Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy. Hermann J, Karmelita-katulska K, Paszkowski J, Drews M, Stajgis M. Diagnosis of a cecal tumour with virtual colonoscopy. Pol J Radiol. 2011;76(2):25-7. Carethers JM. Risk factors for colon location of cancer. Transl Gastroenterol Hepatol. 2018;3:76. doi:10.21037/tgh.2018.09.15. Kunzmann AT, Coleman HG, Huang WY, Kitahara CM, Cantwell MM, Berndt SI. Dietary fiber intake and risk of colorectal cancer and incident and recurrent adenoma in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Am J Clin Nutr. 2015;102(4):881-90. doi: 10.3945/ajcn.115.113282. Aykan NF. Red meat and colorectal cancer. Oncol Rev. 2015;9(1):288. doi:10.4081/oncol.2015.288. Rossi M, Jahanzaib anwar M, Usman A, Keshavarzian A, Bishehsari F. Colorectal cancer and alcohol consumption-populations to molecules. Cancers (Basel). 2018;10(2). doi:10.3390/cancers10020038. Harkins JM, Sajjad H. Anatomy, abdomen and pelvis, sigmoid colon. StatPearls. Additional Reading American Cancer Society. American Cancer Society’s Complete Guide to Colorectal Cancer. Clifton Fields, NE: American Cancer Society. Witmer, L. Clinical anatomy of the large intestine. Harvard School of Public Health. (n.d.). Protein: What Should I Eat? See Our Editorial Process Meet Our Medical Expert Board Share Feedback Was this page helpful? Thanks for your feedback! What is your feedback? Other Helpful Report an Error Submit